Genetic Analysis of Adult Rhabdomyosarcoma

Adult Rhabdomysarcoma (RMS) is a rare cancer with a very poor outcome, compared with RMS in children. Due to the rarity of disease, there is no consensus on how to treat these patients. Recent studies have shown that 2 different genetic abnormalities have been associated with a worse outcome in paediatric RMS. This study aims to determine whether there are any genetic abnormalities associated with a worse outcome in adult RMS. This knowledge may help to treat patients in the future, by identifying those that are at risk of worse outcome and to identify potential targets for treatment with drug therapy.