Radiation-Induced Sarcoma in Survivors of Childhood Cancer

Principle Investigator
Abha Gupta
Date Approved
August 01, 2022
Children with cancer often require radiation treatment (RT) in order to maximize chance of cure. However, RT can be associated with significant long-term effects including growth, organ dysfunction, and as well, risk of second cancers.  One of the most common types of RT-associated second malignancies is sarcoma.  We have identified adults who have sarcoma caused by RT received as a child for pediatric cancer. 
The purpose of this study is to a) describe the treatment of children who developed radiation-induced sarcoma (RIS) as adults; b) describe the outcome of the RIS; c) compare the RT recipes included in protocols used at time of original diagnosis to more contemporary protocols.
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